Polygynax how to properly administer to a girl. Polygynax virgo - instructions for use, analogues, use, indications, contraindications, action, side effects, dosage, composition

Polygynax Virgo is a drug (emulsion) that corresponds to the group of antiseptics and antimicrobials for the treatment of gynecological diseases. This drug is characterized by the following features of the application:

• Sold by prescription only
• During pregnancy: contraindicated
• When breastfeeding: contraindicated

Package

Polygynax Virgo is a local antibacterial and antifungal drug.

Release form and composition

The dosage form of Polygynax Virgo is an emulsion for intravaginal administration in capsules: capsules are soft, oval, with a pointed elongated tip, have a color from light yellow to light brown; the contents of the capsule are an oily emulsion from light yellow to brown (3 capsules in a blister, 1 or 2 blisters in a cardboard box).

Composition of 1 capsule:

• active substances: neomycin sulfate - 35,000 IU, polymyxin B sulfate - 35,000 IU, nystatin - 100,000 IU;
• auxiliary components: hydrogenated soybean oil, dimethicone 1000, Tefoz 63 (esters of palmitic and stearic acids);
• capsule shell: gelatin, glycerol, dimethicone 1000, purified water.

Pharmacological properties

Pharmacodynamics

Polygynax Virgo is designed for use in pediatric gynecology and is a combined drug with antifungal and antibacterial effects.

The drug has bactericidal activity against gram-positive (including Corynebacterium, Staphylococcus aureus, etc.) and gram-negative bacteria (including Escherichia coli, Haemophilus influenzae, Enterobacter aerogenes, Enterococci facium, Proteus vulgaris, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Klebsiella pneumonia, Ureaplasma urealiticum).

The fungicidal action of Polygynax Virgo is directed against pathogenic fungal strains, especially yeast-like fungi of the genus Candida albicans (thrush), cryptococci and histoplasmas.

In addition, the drug helps to improve trophic processes in the vaginal mucosa.

Intravaginal administration of capsules ensures uniform distribution of active ingredients over the surface of the vagina.

Pharmacokinetics

The absorption of Polygynax Virgo into the systemic circulation is insignificant.

Indications for use

According to the instructions, Poligynax Virgo is indicated for use in pediatric gynecology for the treatment of the following diseases:

• vaginitis (nonspecific, fungal, mixed);
• vulvovaginitis;
• cervicovaginitis.

In addition, the drug is used for prevention before surgery in the genital area, as well as before intrauterine diagnostic procedures.

Contraindications

A contraindication to the use of Polygynax Virgo for children is increased sensitivity or an allergic reaction to any of the components of the drug.

Instructions for use Polygynax Virgo: method and dosage

Polygynax Virgo for children is used intravaginally, 1 capsule per day, after the evening toilet, at bedtime. The pointed end of the capsule should be incised and, pressing the capsule, insert its contents into the vagina. The used capsule must be discarded.

Both prophylactic and therapeutic course of application is 6 days, unless otherwise recommended by a doctor.

If you miss a dose of the drug, treatment is continued according to the same scheme.

Side effects

Perhaps the development of allergic reactions.

With prolonged use, there is a risk of developing systemic side effects of aminoglycosides, which increase if the patient has renal failure.

Overdose

With the intravaginal administration of Polygynax Virgo, cases of overdose have not been recorded.

special instructions

During treatment with Poligynax Virgo, you should refrain from using intravaginal tampons. During menstruation, it is recommended to continue the use of the drug.

For impaired renal function

In patients with renal insufficiency, the dose and duration of treatment should be prescribed by the doctor individually.

Use during pregnancy and lactation

The use of the drug during pregnancy is possible only on prescription. In the event that pregnancy becomes known during treatment with Polygynax Virgo, the decision on further therapy should be made by the attending physician.

The use of the drug during lactation is contraindicated.

Application in childhood

drug interaction

Spermicides can reduce the effectiveness of Polygynax Virgo, and therefore their combined use is contraindicated.

Analogues

The analogues of Polygynax Virgo are: Dalacin, Clindamycin, Natamycin, Vagitsin, Nystatin, Clindamycin, Pimafucin, Synthomycin, Clindes, Milagin, Primafungin, Ecofucin, Neotrizol, Cervugid, Meratin, Terzhinan.

Terms and conditions of storage

Store at 15 to 25°C. Keep away from children.

Shelf life - 18 months.

Terms of dispensing from pharmacies

Released by prescription.

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Treatment. Nonspecific, fungal, mixed vaginitis, vulvovaginitis and cervicovaginitis. Prevention: -preoperative prevention of infectious complications during gynecological interventions; - before and after diathermocoagulation of the cervix; - before intrauterine diagnostic procedures; - before childbirth.

Contraindications Polygynax Virgo emulsion caps

Hypersensitivity to any component of the drug. I trimester of pregnancy. Pregnancy and breast-feeding: Use during pregnancy in the II and III trimesters is possible only on prescription in cases where the expected benefit to the mother outweighs the potential risk to the fetus. The lactation period is a contraindication. If necessary, the use of the drug during this period, breastfeeding is stopped.

Method of application and dosage Polygynax Virgo emulsion caps

For intravaginal administration. One capsule after evening dress, before going to bed. Having cut the pointed end, and, slightly pressing on the capsule, insert the contents of the capsule into the vagina. After the introduction of the drug into the vagina, the capsule is thrown into the trash. The course of treatment is 6 days. For the purpose of prevention, the drug is used for 6 days. In case of missing the drug, it is necessary to resume treatment at the usual dose.

1 capsule contains:

active ingredients: neomycin sulfate 35,000 IU, polymyxin B sulfate 35,000 IU, nystatin 100,000 IU

Excipients: Tefoz ® 63, hydrogenated soybean oil, dimethicone 1000;

capsule shell: gelatin, glycerin, dimethicone 1000, purified water.

Dosage form

Vaginal emulsion, in capsules.

Pharmacological group

Antimicrobial and antiseptic agents for use in gynecology. Antibiotics.

ATC code G01A A51.

Indications

Local treatment of vaginitis caused by susceptible microorganisms, including:

• bacterial vaginitis caused by banal pyogenic microflora;
• recurrent nonspecific vaginitis;
• vaginitis caused by fungi of the genus Candida
• vaginitis caused by mixed infection.

Contraindications

Hypersensitivity to the components of the drug (or hypersensitivity to this group of drugs).

Dosage and administration

It is necessary to cut the pointed end of the capsule with scissors. After that, the contents of 1 capsule should be injected intravaginally in the evening before going to bed for 6 days in a row.

Do not stop treatment during menstruation.

Adverse reactions

Local irritation reactions, including redness, swelling, itching of the vaginal mucosa. There may be hypersensitivity in patients to the auxiliary component of the soybean oil preparation. Allergic reactions are possible, including anaphylactic shock, urticaria.

Due to the short custom treatment period of the drug, the risk of systemic toxic effects (for example, on the kidneys, hearing organs) is minimal.

Overdose

There are no reports of an overdose of Polygynax Virgo.

Use during pregnancy and lactation

The drug is intended for use in pediatric gynecological practice.

Children

A special dosage form - Polygynax Virgo - is used in pediatric practice.

Application features

Before prescribing the drug, it is necessary to conduct a bacteriological study. To avoid the transmission of the disease, the patient must be warned about the use of certain personal hygiene products (washcloth, towel), wearing underwear made from natural cotton.

Dosage form Polygynax Virgo is intended for use in children.

The ability to influence the reaction rate when driving vehicles or operating other mechanisms

Does not affect.

Interaction with other drugs and other types of interactions.

There are no data on the undesirable effects of the interaction of the drug Polygynax Virgo with other drugs.

Pharmacological properties

Pharmacodynamics. The properties of the drug consist of the properties inherent in the individual components. Neomycin sulfate is an aminoglycoside antibiotic that has a bactericidal effect by blocking the function of bacterial ribosomes in a wide range of gram-positive and gram-negative microorganisms: Corynebacterium spp., Staphylococcus spp., Mycobacterium tuberculosis, Enterococcus faecium, Escherichia coli, Enterobacter aerogenes, Haemophilus influenzae, Klebsiella pneumoniae, Proteus vulgaris. Polymyxin B sulfate is an antibiotic of a polypeptide nature that acts bactericidal predominantly against gram-negative flora, especially Pseudomonas aeruginosa; strains are also sensitive E. coli, Schigellae, Klebsiellae, Pasteurellae, Serratiae, Staphylococcus spp., Enterobacter, Salmonellae, Haemophilus, Bordetella. Polymyxin B disrupts the osmotic resistance of bacterial membranes and is also active against pathogens that are at rest. Nystatin is a polyene antibiotic that acts fungicidal or fungistatically by binding ergosterol to the cytoplasmic membrane of fungi. Shows activity towards Candida spp., Histoplasma spp., Coccidioides spp., Cryptococcus spp., Aspergillus, Blastomyces dermatidis. Resistance to the active ingredients of Polygynax Virgo develops rarely and slowly.

Dimethylpolysiloxane (dimethicone 1000), contained in the preparation as an excipient, is an organic compound with a high molecular weight that enveloping properties, anti-inflammatory, reparative and anti-allergic action, improves trophic processes in the vaginal mucosa, and also prevents the penetration of the active components of the drug into the mucous membrane.

Pharmacokinetics.

Didn't study.

Basic physical and chemical properties

smooth, oval capsules with a pointed elongated end, from pale yellow to beige.

Shelf life

1.5 years (18 months).

Do not use after the expiry date stated on the package.

Storage conditions

Store in original packaging at a temperature not exceeding 25 ° C.

Keep out of the reach of children.

Package

3 capsules in a blister, 2 blisters in a cardboard box.

Holiday category

On prescription.

Manufacturer

Innothera Chouzy, France.

Location

Rue Rene Chantereau L`Isle Vert, 41150 Chouzy-sur-Cisse, France.

Emulsion for intravaginal administration in capsules - 1 capsule:

• active substance: neomycin sulfate - 35000 IU; polymyxin B sulfate - 35,000 IU; nystatin - 100,000 IU;
• excipients: Tefoz 63® - 143.87 mg; hydrogenated soybean oil - 34.56 mg; dimethicone 1000 - up to 2730 mg;
• capsule shell: gelatin - 768 mg; glycerol - 386 mg; dimethicone 1000 - 175 mg; water - q.s.

Emulsion for intravaginal administration in capsules. 3 caps. in PVC/PVDC aluminum blisters. 1 or 2 bl. in a cardboard box.

Description of the dosage form

Emulsion for intravaginal administration in capsules from light yellow to light brown, soft, oval in shape with a pointed elongated end; the contents of the capsules are an oily emulsion from light yellow to brown.

pharmachologic effect

Antibacterial, antifungal topical.

Pharmacokinetics

When sprayed into the vagina, it is distributed along the walls and envelops them. Does not penetrate through mucous membranes.

Pharmacodynamics

Combined drug, the action of which is due to its constituent components. It has antibacterial, bactericidal and antifungal effects.

Neomycin and polymyxin B are active against many gram-negative and gram-positive microorganisms; Streptococcus spp. and anaerobic bacteria are insensitive to these antibiotics.

Nystatin has a fungicidal effect against fungi of the genus Candida.

Indications for use Polygynax virgo

• cervicitis;
• vaginitis (bacterial, fungal or mixed genesis);
• preoperative prevention of infectious complications during gynecological interventions, before childbirth, during the installation of a contraceptive spiral, during intraurethral studies.

Contraindications to the use of Poligynax virgo

• hypersensitivity;
• pregnancy;
• lactation period.

Polygynax virgo Use during pregnancy and children

Contraindications: pregnancy; lactation period.

Polygynax virgo side effects

allergic contact eczema; with prolonged use - ototoxicity, nephrotoxicity.

Dosage of Polygynax virgo

Intravaginally. 1 caps., after evening dress, before going to bed. Having cut the pointed end, and slightly pressing on the capsule, the contents of the capsule are introduced into the vagina. After the introduction of the drug into the vagina, the capsule is discarded. The course of treatment is 6 days.

For the purpose of prevention, the drug is used for 6 days.

In case of missing the drug, it is necessary to resume treatment at the usual dose.

Precautionary measures

Before using the drug, it is necessary to take a smear and conduct a bacteriological analysis.

We have selected real reviews about the drug Polygynax virgo, which are published by our users. Most often, the review is written by the mothers of young patients, but they also describe a personal history of using the medication on themselves.

Indications for use

Discussion of the drug Polygynax virgo in the records of mothers

My daughter had this problem. Symptoms are similar to yours. We went to the pediatric gynecologist. They did a smear and along the way discovered synechia. The smear showed inflammation. They prescribed polygynax virgo. In the vagina 10 or 14 days. It's certainly tough - to find a vagina in a 3-year-old girl! In the same place, the hymen of the virgins .. It turned out that the medicine was actually squeezed out from the outside. But a second smear showed a significant improvement. After that, synechia was treated with Ovestin for 2 weeks. She passed. They did a swab again. the inflammation is also gone. Co...

Hey, do you have everything? Just recently, Dasha had vulvitis, the piss was red, could it reach the kidneys, does she piss normally? wash with chamomile, do sitz baths, I bought another polygynax virgo, lubricated everything with it

In this case, you can use not candles, but an emulsion, Polygynax, it is produced for children, called Polygynax Virgo. The emulsion will definitely not cause any damage when injected. HPV needs to be clarified - You should undergo screening that reflects the type of virus, that is, genotyping. If I were your doctor, I would get a liquid oncocytology, right after ...

We had this, but we are much older. They prescribed 2 r baths a day of calendula or chamomile, at night Shostakovsky's ointment (vinylin) in the vagina. Good thing Polygynax Virgo is both anti-infection and antifungal. But your baby is so small... I don't know if you can.

Emeni passed, but tell me how did you do the washing? We were also diagnosed with vulvovaginitis, they told us to wash with Miramistin 20 ml, and then inject the emulsion with polygynax virgo, it's scary to imagine how to do it, we are 9 months old... 😢

Rosrachnye, but when we have exacerbations, i.e. there are synechia, there is always a discharge, this is vulvovainitis, there are always a lot of leukocytes in a smear 55-75, but there should be only a few ((((treated polygynax virgo (vulvovaginitis) ... We often have synechia ... and here in April again a little if not complete fusion happened, I compared, again in the spring, as in that year ... I smear ovestin and chamomile baths in the morning and evening for 20 minutes ... we have it due to allergies, plus constipation, i.e. dysbacteriosis, from everything maybe ... but we no longer wear diapers, I used to think that because of them, but .... it grows together without them ((((In your case, I would definitely go to the doctor, even if it passes. ...take a swab...Let...

Polygynax Virgo is indicated for children with characteristic gynecological diseases. What are the indications of Polygynax Virgo for children, and how to take this drug, this article will tell in detail.

In modern pediatrics, there are many childhood diseases, and some of them, oddly enough, belong to the field of gynecology. It is in this area that the use of the medical preparation Polygynax Virgo is relevant.

In pediatric gynecology, there is such a serious disease as bacterial vulvovaginitis, which is accompanied by an acute course of the inflammatory process. That's just right for him effective treatment The French pharmacological company Innotera Shuzy developed the drug Polygynax Virgo, which is specially designed for little girls and teenage girls.

This medical product belongs to the pharmacological group of antibacterial and antifungal agents for topical use in gynecology. The therapeutic effect is achieved due to the activity of the main active substance, which in this case is neomycin sulfate and polymyxin B, nystatin. Dimethicone, Tefoz 63®, hydrogenated soybean oil, gelatin, glycerin and, of course, distilled water are included as excipients in the chemical formula.

If we talk about the effect of this drug in the body, then it should be noted that the polyene antibiotic productively suppresses the vital activity of a number of pathogenic fungi, violating their integrity and preventing reproduction in the affected organism. In addition, there is an extermination of those pathogens that are at rest, but are capable of recurrence.

But the auxiliary component Dimethylpolysiloxane evenly distributes the main active ingredients over the surface of the vaginal mucosa, and also creates favorable conditions for their penetration into all folds. It is also worth noting a pronounced antipruritic effect.

After internal use, neomycin is practically not absorbed from the gastrointestinal tract and is largely excreted from the body unchanged with feces. But with vaginal application, adsorption is almost instantaneous, and the therapeutic effect is noticeable within a couple of hours after direct administration.

Polygynax Virgo is prescribed for children with the following diagnoses: vaginitis, vulvovaginitis, as well as bacterial, fungal or mixed cervicitis. Thus, the external use of the drug is appropriate for infectious and inflammatory lesions caused by neomycin-sensitive pathogens; and also as a reliable prevention of infectious complications in eye surgery.

As for the internal intake, here among the characteristic indications it is worth highlighting infectious and inflammatory diseases of the gastrointestinal tract, as well as preparation for surgery as a bowel cleansing.

This medication demonstrates a mild effect in the body, but not all categories of patients are approved for use. So, contraindications relate to acute intestinal diseases, chronic pathologies of the kidneys and the auditory nerve,.

It is also important to remember that some patients experience hypersensitivity to neomycin, so it is not advisable for them to use this drug during treatment.

Like all medicines, Polygynax Virgo for children has a number of side effects that can develop in a particular clinical picture. In this case, we are talking about many anomalies, because, as you know, the drug has a systemic effect in the girl's body. So, on the part of the urinary system, a pronounced nephrotoxic effect is not excluded, but on the part of the hearing organs, an ototoxic effect is possible.

As for the violations of the digestive tract, the signs of dyspepsia, expressed by nausea, vomiting, diarrhea, may worsen. It is also worth noting that some girls express their complaints regarding allergic reactions, which are represented by skin rash, swelling and severe itching mixed with a burning sensation.

In such cases, it is necessary to temporarily suspend the selected treatment and further application this drug, but on an individual basis, be sure to consult a doctor. A competent specialist in such cases either changes the prescribed therapy regimen or adjusts (reduces) the daily dose of Polygynax Virgo.

It is strictly forbidden to take the drug during pregnancy and lactation, since, as shown by numerous clinical studies, its activity leads to external deformities of the fetus, and is also excreted to the maximum with mother's milk. That is why during these periods it is best to refrain from such an appointment, choosing for yourself a more benign analogue of this pharmacological group.

After all the nuances have been discussed, it is worth moving on to the method of using this antibiotic and daily doses. So, it is necessary to apply it topically in a purely individual dose prescribed by a doctor, based on the existing clinical picture and the age of the patient. When used internally for girls from twelve years old, a single dose is only one gram, while patients 6 to 12 years old are allowed to drink 250-500 mg of this medicine at a time.

The course of treatment can vary from 5 to 10 days, and the maximum dose for local use of Polygynax Virgo should not exceed one gram. Cases of overdose in medical practice have not yet been identified, but it is still better not to violate the prescribed treatment regimen.

Among the special indications, it is worth emphasizing that in case of impaired functioning of the kidneys and liver, as well as in the case of neuromuscular diseases and hearing impairment, it is worth prescribing this medicine with caution.

In addition, it is necessary to measure the feasibility of such therapy in case of extensive damage to the skin, but in the case of perforation of the eardrum, the indicated remedy can provoke partial or complete hearing loss. Also, do not combine with other drugs, since the clinical outcome of such "pharmacological combinations" has not yet been scientifically studied.

So Polygynax Virgo is a powerful medicine, but it is strictly forbidden to take it by means of superficial self-medication for all categories of patients, especially when it comes to little girls.

One of the most common problems of visiting a pediatric gynecologist is bacterial or fungal vulvovaginitis. In the treatment of such a disease, various means are used, among which Polygynax can be called. How does such a French medicine work, is it used in children, and how to properly deliver it to a child?

Release form and composition

Polygynax is presented in pharmacies in two types:

• Vaginal capsules. They are oval in shape and yellowish or beige in color. Inside the capsule is a yellow-brown semi-liquid mass. Such a medication is sold in blisters of 6 pieces, and in one pack there are 6-12 capsules.
• emulsion, which is administered intravaginally. This form of the drug is called Polygynax Virgo. The emulsion itself, like the contents of the vaginal capsules, is a semi-liquid substance of a yellow-brown hue. It is also placed in a soft oval yellow-brown capsule, but such a capsule has an elongated pointed end. The drug Virgo is sold in blisters of 3 pieces, and one pack contains 3-6 capsules.

The action of both drugs provides a complex of three active substances:

1. Neomycin. Such a component in the form of sulfate is presented in 1 capsule with a dosage of 35 thousand IU.
2. Nystatin. The dosage of this ingredient in each capsule of Polygynax and Virgo is 100,000 IU
3. Polymyxin B. The amount of this substance in the form of sulfate per 1 capsule is 35,000 IU.

Additionally, capsules include soybean oil, dimethicone, gelatin and some other substances.

Operating principle

Due to the presence of antibacterial and antifungal components in the composition, Polygynax effectively destroys different types microorganisms, including candida. In addition, the drug has a positive effect on the trophic processes occurring in the mucous membrane of the genital tract. After entering the vagina the drug acts only locally and is almost not absorbed.

Indications

Polygynax and Virgo are used for gynecological diseases caused by drug-sensitive pathogens. The tool is in demand in the treatment of:

• fungal vaginitis;
• nonspecific vaginitis;
• vaginitis caused by several microorganisms;
• vulvovaginitis;
• cervicovaginitis.

In addition, Polygynax is prescribed before an operation or diagnostic procedure in the vagina or cervix.

At what age are they prescribed?

Polygynax capsules in children are usually not used, since such a medication should be injected deep into the vagina, which is often impossible for girls.

Polygynax Virgo is called the children's form, since this medicine can be used in girls and teenage girls.

It is not contraindicated at any age, so it is prescribed for both children of the first years of life (for example, a baby of 11 months), and girls of preschool or school age.

A single dose of the drug is the contents of one capsule. The duration of application is usually 6 days.

If the next dose is accidentally missed, the next day you do not need to use 2 capsules, but you should simply continue treatment at the dosage prescribed by your doctor.

Terms of sale and storage

To purchase Poligynax Virgo in a pharmacy, you need to get a prescription from a doctor.

The average price of 6 capsules with emulsion is 500 rubles. Store the drug at home is recommended at room temperature. The shelf life of the drug is 2 years.

In contact with

Classmates

The treatment of many gynecological problems requires local action of drugs, in which conventional pills cannot help. For application directly to the vaginal mucosa, ointments, creams are used, and vaginal suppositories are the most convenient form. This type of drug makes it possible to influence directly the focus of the problem, strictly observe the dosage and maintain the effect for the maximum possible time. To combat infection by pathogenic microorganisms and fungi different kinds French candles-capsules Polygynax are often used.

The product is represented by special suppositories-capsules, which are intended for vaginal administration. It is soft in texture, oval, has a color from pale yellow to rich beige. There are three substances among the active ingredients at once, which explains such a wide spectrum of activity of the drug: neomycin sulfate (a first-generation antibiotic with a wide spectrum of action), polymyxin B sulfate (an antibiotic that acts mainly on gram-negative microorganisms) and nystatin (antifungal agent). Among the excipients are soybean oil, dimethicone and tefoz 63. The candle capsule itself is made from gelatin, glycerol and dimethicone.

Polygynax is used in gynecology and has an antibacterial and antifungal type of effect. Its activity is shown against both gram-positive, and gram-negative microorganisms. As for fungi, the remedy will be relevant against the genus Candida, Cryptococus and Histoplasma. In addition to its main action, suppositories normalize trophic processes that take place in the mucous membrane of the female vagina. After the introduction, the capsule dissolves, and its contents are evenly distributed over the surface of the mucosa, exerting its local effect. It is practically not absorbed into the systemic circulation.

Indications for the use of vaginal suppositories

Given the properties of the drug discussed above, you can specify the list of ailments and problems with which it helps to cope. So, the main purpose of suppositories is the therapy of inflammatory diseases of an infectious nature, including:

• vaginitis of nonspecific type;
• inflammation of the vaginal mucosa under the influence of the activity of pathogenic fungi;
• mixed vaginitis;
• vulvovaginitis;
• cervicovaginitis (a combination of inflammation of the vaginal mucosa and cervix).

In some cases, capsules can be prescribed for cystitis, especially in its complicated and chronic forms. Also, the agent can be used as a prophylactic to prevent the development of inflammatory processes, which is especially important before a planned operation in the localization of the genital organs, before and after the procedure for cauterization of cervical erosion, before diagnostic procedures that are implemented intrauterine, as well as before childbirth.

Instructions for use and dosage

Capsules of the drug in question are administered at bedtime, 1 piece for 12 days as part of a therapeutic course, and for 6 days - when infection is prevented. To get the best result of treatment, you need to follow some simple rules:

• before proceeding with the procedure, you need to wash your hands well with warm water, but without the use of soap and other detergents;
• it is better to inject the prepared capsule in the supine position, slightly pushing it into the vagina with your finger (it is recommended that the insertion depth be equal to the length of the finger, otherwise the dissolved drug may simply leak out of the capsule or the capsule, even having dissolved, will come out);
• it is advisable not to rise from a lying position for at least a third of an hour in order to ensure maximum safety of the drug;
• after the procedure, it is worth putting on a sanitary pad, since the allocation of part of the product is normal.

It should be noted that exceeding the recommended terms of drug use will negatively affect its effectiveness. A clear limitation of the course exists so that pathogens do not develop resistance to the active substances of the drug, and there is no re-infection. Another important point is that latex condoms should not be used during sexual intercourse therapy. During the monthly course of therapy, it is not worth interrupting, despite the discharge, you can continue to administer the capsules. But the intake of alcoholic beverages during treatment should be completely abandoned. It is important to know that if one or more doses of the drug are missed, it is necessary to start the course of therapy or prevention again.

How to use to treat thrush

Vaginal capsules are also relevant for use in the case of thrush, since this disease is provoked by a fungus of the genus Candida. For the treatment of this ailment, suppositories with an average dosage of the active substance (Polygynax 10) are used, but if the symptoms do not reduce their activity for several days, then they switch to the maximum dosage - Polygynax 12. The treatment period is 12 days, and it is worth going through it completely, not stopping earlier, even if all the symptoms that cause discomfort no longer manifest themselves - otherwise, a repeated outbreak of fungal activity is possible.

For prevention

Based on what the drug in question is prescribed for, it is easy to imagine the range of problems that can be prevented with the help of the drug. So, in order to prevent inflammatory and infectious processes, the capsules are also administered once a day at bedtime, but the course is 6 days without interruption, and the dosage of the drug used should be minimal (Polygynax 6).

Application of Poligynax Virgo for girls

This tool is designed specifically for girls and adolescents who are not yet sexually active. The drug Virgo is presented in the form of capsules, the liquid content of one is intended for one procedure. So, the main nuances are hidden in the question of how to administer the remedy to a child. It is necessary to carry out a therapeutic event in the evening, after the last toilet, immediately before bedtime. The pointed end of the soft capsule should be incised, directed into the vagina and carefully squeezed out all the contents. After the procedure, the used capsule is discarded. The course of treatment, as well as the prophylactic course for girls, is only 6 days, but without gaps and breaks.

Polygynax during pregnancy

It is worth noting that the use of any drugs during the bearing of a baby should be made only with the permission and appointment of a doctor. The manufacturer claims that Polygynax capsules do not have any negative impact on the fetus, therefore, if necessary, they are allowed to be used, but in a minimum dosage.

One of the indications for the use of the product is the prevention of the development of infectious and inflammatory diseases before childbirth, but it is worth clarifying that such preventive measures relevant only if the pathogenic microflora of the vagina was detected in a pregnant woman through laboratory tests. During lactation, the use of this drug is not recommended; if indicated, doctors usually select other means.

Contraindications and side effects

The tool, despite its multicomponent nature, has few contraindications for use. First of all, this is hypersensitivity and intolerance to the components of the composition of the drug, and secondly, the first trimester of pregnancy. It is also not recommended to use during breastfeeding, as mentioned above. If there is an urgent need to use the remedy, then lactation is temporarily stopped.

As for possible side effects, in some cases there are pronounced allergic responses, both local and systemic, there may be a burning sensation, itching, irritation of the mucous membrane. With prolonged use, side effects may increase in intensity. Overdose situations have not been reported to the manufacturer, so there is no such information.

Are there analogues cheaper?

Polygynax vaginal capsules are quite an expensive drug, and this is largely due to the country of production - in this case, France. There is a Russian analogue, the closest in composition called Terzhinan. It contains the same nystatin and neomycin sulfate, but in addition, ternidazole (an antifungal component) and prednisolone (has a pronounced anti-inflammatory and anti-allergic effect) are included in the number of active components. As part of this, there is an important question - which is better Terzhinan or Polygynax? In general, the range of their use is the same, as is the effectiveness, but in some cases Terzhinan can give a more pronounced anti-inflammatory effect. So the drug in general can be called equivalent, and which one is better to use will be determined by the doctor.

There are no complete analogues of the remedy, in addition to its variety Virgo. It is possible to identify several effective drugs, which also help fight inflammatory and infectious processes in the gynecological field, but have other active substances: Vagitsin, Clindes, Milagin, Pimafucin, Primafungin.

Video about the use of the drug Polygynax in gynecology

In this video, the gynecologist informs patients about the scope and aspects of the activity of Polygynax suppositories. The video material provides detailed information on the main aspects of the use of the product in the framework of therapy and prevention.

Patient reviews about candle treatment

Allah: The drug is good, I was prescribed for vaginitis. Has passed or has taken place a course, and recovery successfully has come.

Sveta: For me, these capsules are expensive, I asked the doctor for a simpler analogue to prescribe, but they told me that these are the ones I need. I recovered, but it hit my pocket.

Ilona: Alas, they didn’t fit me, a terrible itch began, I had to immediately stop the procedures.

Marina: I really liked the drug! No discomfort, comfortable use and good results!

Pathological discharge from the genital tract and itching are the first symptoms that speak in favor of an inflammatory reaction. But an accurate diagnosis is impossible without examination. For diagnosis at the initial stage, it is enough to visit a gynecologist so that he takes a smear on the vaginal microflora.

When it's time to heal

The vagina is an environment with a certain balance of many microorganisms. Any changes in the flora are accompanied by the appearance of a certain type of secretions. Normally, the amount of discharge from the vagina is insignificant. A healthy woman hardly notices them. Excretions can intensify:

• during the period of ovulation;
• before menstruation;
• in pregnant women;
• with sexual arousal.

AT reproductive age in 70% of cases, the appearance of noticeable discharge - whiter - is associated with inflammation. This changes the composition of the microflora of the vagina.

Opportunistic pathogens are present in most people. But it is not their quantity that matters, but the ratio with beneficial microorganisms. At healthy women in smears, single cells of opportunistic flora can be determined. The table shows the normal and pathological results of a vaginal smear.

Table - The state of the biocenosis of the vagina

Active ingredients of the drug

Candles "Polygynax" contain three active ingredients that can cope with several types of infection at the same time:

• neomycin sulfate;
• polymyxin B sulfate;
• nystatin.

Neomycin sulfate

It is an antibiotic from the group of aminoglycosides, has a wide spectrum of action. In small concentrations, it has a bacteriostatic effect. At the same time, it penetrates the microbial cell, binds to specific receptors and stops protein synthesis. Bacteria lose their ability to reproduce.

In high concentration it has a bactericidal effect. Neomycin causes direct damage to the cell membrane of the microbe, which leads to its death. Activity is manifested against the following microorganisms:

• streptococci;
• staphylococci;
• coli;
• salmonella;
• shigella;
• corynebacter;
• Proteus.

Polymyxin B sulfate

Polypeptide antibiotic with bactericidal action. It attaches to the bacterial membrane, increases its permeability, which leads to cell decay. Drug resistance develops very slowly. Effective against the following microorganisms:

• coli;
• salmonella;
• shigella;
• klebsiella;
• bordetella;
• enterobacter;
• pseudomonas;
• haemophilus influenzae.

An antifungal agent from the group of polyene antibiotics. The peculiarity of the mechanism of action is based on the ability to integrate into the membrane of the fungus. In this case, a channel is formed through which water and electrolyte ions freely penetrate into the cell. Gradually, this leads to the disintegration of the fungal cell.

Fungi of the genus Candida are sensitive to nystatin. Has no effect on the following microorganisms:

• bacteria, including gardnerella;
• viruses;
• protozoa (Trichomonas).

When is it necessary and when is it contraindicated?

Indications for the use of Poligynax suppositories include treatment and prevention. With a therapeutic purpose, it is prescribed for the following conditions:

• nonspecific vaginitis - inflammation caused by opportunistic flora;
• fungal vaginitis - when the thrush is supplemented by microbial flora;
• mixed vaginitis - a diverse flora was found in the smear;
• vulvovaginitis - inflammation spread to the vestibule and the vaginal cavity;
• cervicovaginitis is an inflammatory reaction in the cervical canal and vagina.

With chlamydia, the use of Polygynax suppositories can only be part of complex treatment.

Infection prevention

For the purpose of prevention, "Polygynax" is prescribed in cases where it is necessary to prevent the reproduction of conditionally pathogenic flora. Most often, these conditions are associated with various manipulations on the genitals.

• Preparation for the operation. If a woman is preparing for a planned operation on the genitals, then a week in advance, you can start using candles. This is especially true with a smear with a second or third degree of purity, when there is a slight inflammation, but after surgery it can become a source of infection.
• Preparing for childbirth. The newborn enters from an almost sterile environment through the vagina, rich in various microorganisms, into the outside world. Weakened local immunity during pregnancy leads to the activation of conditionally pathogenic flora. Often pregnant women are forced to use suppositories for most of their pregnancy. A week before the planned date of childbirth, both natural and induced, Poligynax can be used with caution. But only thrush is not an indication for the appointment, it must be combined with elevated leukocytes and bacterial flora in the smear.
• diagnostic manipulations. Some invasive diagnostic methods can lead to ascending infection from the vagina. Diagnostic curettage, hysteroscopy should be performed with a sanitized vagina.
• Treatment of the cervix. If a decision is made to treat cervical erosion by diathermocoagulation, then it is necessary to create a clean environment in order to avoid infection of the resulting wound. Therefore, prevention is carried out before and after manipulation.

When a different medicine is needed

Not in all cases, the use of "Polygynax" is allowed. Contraindications include the following conditions:

• individual intolerance;
• first trimester of pregnancy;
• breastfeeding period.

Instructions for the use of candles "Polygynax"

Before undergoing a course of treatment, it is necessary to pass a smear on the microflora of the vagina. Vaginal tablets "Polygynax" are not used only for thrush. It is necessary to have a co-infection in order to have a point of application for antibiotics.

1. In the evening, carry out hygiene procedures.
2. Remove the capsule with clean hands.
3. It is necessary to introduce Polygynax suppositories in the supine position deep into the vagina.
4. Wash the hands.

Unwanted Effects

Side effects of "Polygynax" manifest themselves in the form of local reactions:

In this case, you need to stop using the drug and report the reaction to the doctor. But doctors' reviews show that such reactions rarely develop if the instructions are followed correctly.

The duration of application also needs to be regulated. It is not recommended to use more than the period specified in the instructions. Aminoglycosides are able to enter the systemic circulation in a small amount, which will lead to the appearance of their side effects.

The analogues of "Polygynax" are "Amintax" and "Polygynax Virgo". The first of them has a similar composition, but is produced in Russia, unlike the original drug, which is produced in France. "Polygynax Virgo" is a dosage form intended for use in virgins. The capsule has a pointed end that is cut off. Through it, the contents of the capsule are gently squeezed into the vagina. Reviews of the candles "Polygynax" talk about the effectiveness of treatment with this drug.

Reviews: "I didn't fit"

It turned out that, having chilled the appendages, I didn’t find time for myself to immediately go to the doctor, so I probably would have lived with pain in the lower abdomen, if at one moment I hadn’t twisted so that I couldn’t unbend. I had to go. The diagnosis was not comforting, my inflammation developed into a chronic form. Ultrasound showed that the ovaries stuck to the uterus with adhesions because of this, such pains during walking and exertion. There was an offer to go to the hospital, which I refused, then a day hospital and warming up, the same refusal, since I have small children and there is no one to leave them with.

Discharged treatment at home. There were many injections of antibiotics, then all sorts of douches and pills. All this lasted a month and a half. After all this, at the doctor's appointment, I was prescribed Polygynax vaginal suppositories for the completion of treatment.
The candles were unusable. They treat inflammation and thrush right away. The composition includes a group of antibiotics and nystatin. I was very pleased with this, since thrush cannot be avoided from such a dose of antibiotics. The drug is prescribed for fungal, mixed vaginitis, from inflammation of the appendages, before surgery. They can also be taken for prevention. If I had known about them earlier, I would not have started my inflammation. Now they are always at home.

In total, I used this drug 2 times: the 1st course was prescribed during pregnancy; 2nd - at a scheduled medical examination. Antibacterial suppositories "Polygynax" was first prescribed to me by a gynecologist for the treatment of thrush during pregnancy (by the way, thrush can occur as a reaction of the body to taking OK), but the course of treatment gave only a temporary (short) positive effect, then the thrush returned. The second time I was prescribed these suppositories after a routine examination by a gynecologist (after passing tests, the results of which the doctor did not particularly like). I didn’t have any complaints about my well-being, but the doctor decided to prescribe a course of Polygynax for prevention. I, as an obedient patient, bought these candles and completed the course. And after a couple of days, I started having a wild thrush, which I treated in a complex (pills + candles) with Pimafucin. The drug "Polygynax" categorically did not suit me. Still, antibiotics greatly disrupt (and destroy) the microflora of the mucous membranes, so they can be treated only as prescribed by the doctor and his own control (which can correct the therapy with a negative effect).

Nancy K, http://otzovik.com/review_879203.html

Spent a full course - 12 candles. They prescribed it because of inflammation (a lot of leukocytes), and vaginal dryness, no discomfort, everything is as always with suppositories. I put it in at night - in the morning a hygienic shower. Candles, of course, partially flow out, they also melt from body temperature. The entire course went in pads and at night - too. At night, so that there is no leakage of candles, and during the day, the drug also partially comes out. I agree that the first step is to read the manual. Lived without sex and alcohol for 12 days. Treatment is treatment. Today I was at the gynecologist, she was in shock - the mucosa is in order, there is no redness. She took a smear - she says it should be normal. So I have no complaints about polygynax! I had experience of treatment with Ovestin suppositories, so they almost burned everything there exactly 10 minutes after insertion inside and everything itched and itched. This is not the case with polyjenax. After polygynax, I put Ovestin - I went without any problems at all, I think Ovestin burned because of inflammation, which polygynax defeated! Health, you girls, and do not delay pregnancy, because it may be too late. Infertility is a terrible diagnosis both for the body and especially for the soul!

Most gynecological problems require local treatment during treatment. medications. In solving these problems, the use of conventional tablets is simply powerless.

For such purposes, ointments and creams are usually used, but the most convenient is the use of intravaginal suppositories. Medicines of this type have an impact directly on the problem itself, with precise dosage compliance and long-term preservation of the effect.

In order to combat infection with pathogenic bacteria and various fungal pathogens, Polygynax vaginal suppositories from a French manufacturer are often used.

The composition and properties of candles Polygynax

The medicine is produced in encapsulated form. Capsules are used for vaginal treatment. They are soft to the touch, have an oblong shape, the color of the shell varies from light yellow to beige.

The drug has high efficiency, which is explained by the presence of three main substances at the same time in the composition: nystatin, which has antifungal properties, polymyxin B sulfate, which is an antibiotic aimed at eliminating gram-negative bacteria, and neomycin sulfate, which belongs to the tetracycline antibiotics and is the owner of a fairly large range actions.

In addition to them, there are additional substances inside the capsules: tefoz 63, dimethicone and soybean oil. In the manufacture of the capsules themselves, dimethicone, glycerol and gelatin were used.

The drug is widely used in the treatment of gynecological diseases, has an effective effect on bacteria and fungi. Its action is aimed at eliminating gram-negative and gram-positive representatives of pathogenic microflora.

Eliminates fungal pathogens belonging to the genera: Histoplasma, Cryptococus and Candida. Along with this, suppositories stop the flow of trophic processes on the mucous surfaces of the internal genital organs. After some time, after the introduction of the capsule into the vagina, its shell dissolves.

The active substance that is inside is distributed evenly along the walls of the vagina, having a direct effect on pathogenic microorganisms. Substances present in the medicine almost do not enter the bloodstream.

Who is shown to use

If infectious and inflammatory processes provoked by pathogenic microflora are detected, the doctor will prescribe a course of treatment with intravaginal suppositories, which contain an antimicrobial antibiotic.

Polygynax is prescribed for:

• fungal vaginitis, which has a non-specific type;
• vaginal candidiasis;
• vulvitis and vulvovaginitis;
• cervicovaginitis;
• prevention of the development of infections and inflammation of the genital organs;
• sanitation of the birth canal;
• preparation for the diagnosis of the intrauterine space;
• prenatal preventive measures;
• preparation for a surgical operation performed on the female reproductive organs;
• preparation for cauterization on the cervix and after it.

This remedy is rarely prescribed by a doctor for the treatment of chronic cystitis or complications caused by it.

How to apply and in what doses

Polygynax capsules should be injected one at a time into the vagina. The procedure is recommended to be carried out at bedtime, for twelve days, during a course of treatment and six days for prevention.

The most effective result of the application will be subject to a few simple recommendations:

• before you enter the capsule, you must wash your hands with warm water, without using hygiene products - without soap;
• The capsule must be administered while lying down. It must be gently pushed with a finger into the vagina and deepen the drug to the length of the finger - this is the optimal depth of the capsule. With insufficient depth, the medicine from the capsule is able to leak out or the capsule itself will come out without dissolving;
• upon completion of the procedure, it is necessary to lie down for 20-30 minutes, during this time the shell will dissolve and the contents will be distributed over the surface of the vagina;
• after the injection of the medicine, it is necessary to use a sanitary napkin, because usually part of the drug comes out.

It is necessary to focus on the fact that longer use of the remedy can adversely affect its effectiveness. The period of use is limited due to the development of resistance of pathogenic microflora to the active substances of the medicinal product.

During treatment with Polygynax, latex condoms should not be used. The course of treatment during menstruation cannot be interrupted, capsules can be administered despite the discharge. During treatment, it is advisable to refrain from taking drinks containing alcohol.

Important. Having missed just one procedure, treatment or prevention must be started all over again.

The manufacturer has provided for the release of a special form of the drug called Polygynax Virgo - virgo in Latin means virgin, maiden, intended for the treatment of girls and adolescents. The tool is produced in special capsules, with a pointed tip. Before the introduction, it is required to cut it off with scissors, then insert it into the vagina and squeeze out all the contents, and dispose of the empty capsule.

Treatment with Polygynax during pregnancy and lactation

The use of any medication during pregnancy is allowed only if they are prescribed by a doctor. The manufacturer of vaginal suppositories Polygynax claims that they are completely safe for the fetus. Based on this, they are allowed to be used, in case of urgent need, in minimal doses.

Indications for the appointment of funds are preventive measures aimed at preventing the development of inflammatory and infectious processes in the prenatal period. Such measures make sense only if the presence of pathogenic microflora is detected in the analyzes of the future mother, which must be confirmed by laboratory tests.

During breastfeeding, treatment with this medication is not recommended. Usually, when pathogenic microflora is detected, doctors prescribe treatment by other means.

Contraindications and side effects

The preparation contains antibiotics, to which the body quickly adapts. Because of this, women using these suppositories usually do not show side effects.

To date, not a single fact of overdose has been identified, but with long-term use, manifestation is possible:

• an allergic reaction to substances present in the composition;
• local irritation or itching;
• side effects of aminoglycosides.

If the listed deviations appear, you should immediately seek the advice of a specialist.

The drug has a fairly minimal list of contraindications. It is limited to individual intolerance to the components of the drug and the first three months of pregnancy. In addition, it is impossible to carry out therapeutic measures during breastfeeding. If there is an urgent need for treatment with this particular drug, breastfeeding should be stopped for a while.

Drug analogues

Polygynax vaginal suppositories have a wide variety of analogues, cheap and expensive.

It affects representatives of the simplest microflora, aerobic and anaerobic organisms. It is used most often in the treatment of trichomoniasis, a variety of vaginitis and other infections. It is used as a preventive measure before surgery.

Neo-Penotran

It has antiprotosic and antimicrobial action. It is prescribed for diseases caused by fungal pathogens, vaginitis, and infections that develop as a result of mixing the vaginal microflora. This drug has Russian counterparts that are not inferior to the original in effectiveness:

Has an antiseptic effect. It is prescribed during preventive measures before childbirth and abortion, operations on the internal genital organs, with sexually transmitted diseases, vaginitis.

Candles with Nystatin

It has a detrimental effect on pathogens of fungal diseases. They treat candidiasis.
Doxycycline - the drug is used in the treatment of pathologies of the respiratory organs, acute and advanced pathologies of the prostate and gonorrhea.

Restores the microflora of the vagina, improves immunity. It is used in combination with other drugs during the treatment of gynecological diseases that destroy the vaginal microflora. Recommended in the treatment of vaginal dysbiosis.

Antibacterial, antiviral medication, enhances the protective properties of the body. It is often prescribed for the treatment of urogenital diseases and pathologies of the genital organs, of infectious origin: candidiasis, herpes, trichomoniasis, mycoplamosis, ureaplamosis, diseases of the uterus, vulvovaginitis, prostatitis and urethritis.

Russian-made analog medication. The drug also contains nystatin and neomycin sulfate. In addition to these ingredients, it includes ternidazole, which has anti-fungal properties, and prednisolone, which has anti-inflammatory and anti-allergic characteristics.

More information about Polygynax candles and their application - on the video:

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Re: Vaginal suppositories Polygynax, with what symptoms.

They are already outdated, the gynecologist told me that the pathological flora no longer reacts to these suppositories, resistance has developed. Elzhina is prescribed to me, it helps very well from various infections

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